Design, Synthesis and Antiviral Activity of 2-(3-Amino-4-piperazinylphenyl) chromone Derivatives
MK Kim, H Yoon, DL Barnard, Y Chong
Index: Kim, Mi Kyoung; Yoon, Hyunjun; Barnard, Dale Lynn; Chong, Youhoon Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 4 p. 486 - 488
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Abstract
Previously, we have confirmed that the antiviral activities of the chromone derivatives were controlled by the type as well as the position of the substituents attached to the chromone core structure. In the course of our ongoing efforts to optimize the antiviral activity of the chromone derivatives, we have been attempting to derivatize the chromone scaffold via introduction of various substituents. In this proof-of-concept study, we introduced a 3- ...
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