The Journal of Organic Chemistry

Quinone methide p-hydroxybenzylation of 1, 3-diketones

AJ Poss, RK Belter

Index: Poss, A. J.; Belter, R. K. Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 891

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Citation Number: 12

Abstract

The Michael addition of 1, 3-diketones to unsaturated compounds is well documented and has been extensively utilized in the preparation of natural products.'Quinone methides are conjugated homologues of vinyl ketones but are more reactive due to the additional driving force of aromatization after conjugate addition. The application of these highly conjugated intermediates to the formation of carbon-carbon bonds is limited by the stability of the ...

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