Synthesis of New Glycerolipids Linked to Hydroxamate Derivatives Designed for Two??Dimensional Crystallization of Aminopeptidase M

JM Altenburger, L Lebeau, C Mioskowski…

Index: Altenburger, Jean-Michel; Lebeau, Luc; Mioskowski, Charles; Schirlin, Daniel Helvetica Chimica Acta, 1992 , vol. 75, # 8 p. 2538 - 2544

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Citation Number: 9

Abstract

Abstract The synthesis of glycerolipids linked to hydroxamate derivatives designed for two- dimensional crystallization of aminopeptidase M is reported. The lipid moieties are readily obtained using a convergent pathway. Their structure allows the introduction of a wide variety of ligands of biological interest.