Tetrahedron letters

A mild and effective iodination method using iodine in the presence of bis-(trifluoroacetoxy) iodobenzene

R Benhida, P Blanchard, JL Fourrey

Index: Benhida, Rachid; Blanchard, Pierre; Fourrey, Jean-Louis Tetrahedron Letters, 1998 , vol. 39, # 38 p. 6849 - 6852

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Citation Number: 61

Abstract

Herein is described a mild and effective iodination method using bis-(trifluoroacetoxy) iodobenzene-iodine as reagent to be applied to electron deficient heterocyclic systems (protected indoles, coumarin…) Moreover, sensitive protecting groups such as acetyl and tert-butyldimethylsilyl were found to be stable under the new iodination reaction conditions.