Synthesis of 2??Arylquinazolin??4 (3H)??ones by N??Aryl Benzamidines with Aromatic Carbonates

S Aikawa, C Sekiguchi, Y Yamazaki…

Index: Aikawa, Shunichi; Sekiguchi, Chiharu; Yamazaki, Yuko; Hattori, Mika; Isaka, Tatsuya; Yoshida, Yasuhiko; Ihara, Shogo Journal of Heterocyclic Chemistry, 2014 , vol. 51, # 2 p. 343 - 348

Full Text: HTML

Citation Number: 3

Abstract

Abstract The reaction of N-aryl benzamidines with diphenyl carbonate or ethyl phenyl carbonate synthesized 2-arylquinazolin-4 (3H)-ones in simple and safe process with good yields (71–90%). It was suggested that different electron-donating substituent in N-aryl benzamidines afforded similar effect to the yields of 2-arylquinazolin-4 (3H)-ones. In these reactions, N-aryl benzamidines built up intermediate compounds by nucleophilic addition ...