Phosphoryl Chloride Mediated Synthesis of 5-Arylidene-2, 4-Thiazolidinediones Derivatives via Aromatic Bisulfite Adducts

S Mohanty, A Chandra Karmakar

Index: Mohanty, Sandeep; Reddy. G, Sandeep; Karmakar, Arun Chandra Letters in Organic Chemistry, 2014 , vol. 11, # 3 p. 197 - 202

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Citation Number: 3

Abstract

The carbon-carbon bond formation by the condensation of bisulfite adduct of aromatic aldehydes with thiazolidine-2, 4-dione to furnish 5-arylidene-2, 4-thiazolidinedione's has been investigated. This novel methodology was applied to convert substituted aryl bisulfite adducts to corresponding 5-arylidene-2, 4-thiazolidinedione's with POCl3 in less-polar solvents such as toluene, chlorobenzene and o-xylene. 5-(4-methoxybenzylidene) ...