Synthesis and hydrolysis of bicyclic 2-imino-2, 5-dihydrofurans fused to a pyridine ring

…, LV Karapetyan, MD Tadevosyan

Index: Avetisyan; Karapetyan; Tadevosyan Russian Journal of Organic Chemistry, 2010 , vol. 46, # 8 p. 1259 - 1261

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Citation Number: 2

Abstract

Numerous fused pyridine derivatives are widely used in medicine as cardiotonics [1] and antiphlogistic agents [2]. Functionally substituted derivatives of unsaturated γ-lactones are widespread in nature, and they often exhibit pronounced biological activity. Apart from monocyclic unsaturated γ-lactones, derivatives of spiro and fused bicyclic systems are present in natural sources [3–6]. Taking into account that nitrogen-containing analogs of ...

Metalation of pi-deficient heterocycles a facile synthesis of cerpegin

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One-pot three steps synthesis of cerpegin

[Villemin, Didier; Liao, Liang Tetrahedron Letters, 1996 , vol. 37, # 48 p. 8733 - 8734]

'One-pot'four-step synthesis of cerpegin

[Lazaar, Jalal; Hoarau, Christophe; Mongin, Florence; Trecourt, Francois; Godard, Alain; Queguiner, Guy; Marsais, Francis Tetrahedron Letters, 2005 , vol. 46, # 22 p. 3811 - 3813]