Copper (I)??Catalyzed Aerobic Oxidative Azide–Alkene Cyclo??addition: An Efficient Synthesis of Substituted 1, 2, 3??Triazoles
…, WC Chen, C Ramesh, T Kotipalli…
Index: Janreddy, Donala; Kavala, Veerababurao; Kuo, Chun-Wei; Chen, Wen-Chang; Ramesh, Chintakunta; Kotipalli, Trimurtulu; Kuo, Ting-Shen; Chen, Mei-Ling; He, Chiu-Hui; Yao, Ching-Fa Advanced Synthesis and Catalysis, 2013 , vol. 355, # 14-15 p. 2918 - 2927
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Citation Number: 20
Abstract
Abstract: A novel, copper (I)-promoted azide–alkene aerobic oxidative cycloaddition protocol was developed for the regioselective synthesis of 1, 4-disubstituted/1, 4, 5-trisubstituted 1, 2, 3-triazoles by using azides and electron-deficient olefins under an oxygen atmosphere. Keywords: aerobic oxidation; azide–alkene cycloaddition; copper catalysis; 1, 2, 3-triazoles
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