Cobalt-Catalyzed Carbocyclization of o-Iodobenzaldehydes and o-Iodophenylketones with Alkynes
KJ Chang, DK Rayabarapu, CH Cheng
Index: Chang, Kuo-Jui; Rayabarapu, Dinesh Kumar; Cheng, Chien-Hong Organic Letters, 2003 , vol. 5, # 21 p. 3963 - 3966
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Citation Number: 55
Abstract
Treatment of various o-iodobenzaldehydes and o-iodophenyl ketones with alkynes in the presence of Co (dppe) I2 and Zn powder in acetonitrile at 80° C afforded the corresponding indenols in moderate to excellent yields with exceedingly high regioselectivity. For most unsymmetrical alkynes tested, the carbocyclization gave a single regioisomer.
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