Elsamicins A and B, new antitumor antibiotics related to chartreusin. 2. Structures of elsamicins A and B

…, M Tsunakawa, M Konishi, H Kawaguchi…

Index: Sugawara, Koko; Tsunakawa, Mitsuaki; Konishi, Masataka; Kawaguchi, Hiroshi; Krishnan, Bala; et al. Journal of Organic Chemistry, 1987 , vol. 52, # 6 p. 996 - 1001

Full Text: HTML

Citation Number: 35

Abstract

The structures of new antitumor antibiotics elsamicins A (la) and B (lb), produced by an unidentified actinomycete strain 5907-21, have been established by a combination of chemical degradation, spectral analysis, and X-ray diffraction. They are structurally similar to chartreusin containing chartarin as an aglycon, but differ to each other in sugar moieties. Elsamicin A possesses two novel sugars, 2-amino-2, 6-dideoxy-3-O-methyl-~ galactose ...