Journal of the American Chemical Society

Temperature dependence of carbene-carbene rearrangements. A new method for the generation of carbenes

UH Brinker, J Ritzer

Index: Brinker, Udo H.; Ritzer, Joachim Journal of the American Chemical Society, 1981 , vol. 103, # 8 p. 2116 - 2119

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Citation Number: 41

Abstract

Acknowledgment. This investigation was supported by Grant CA 21 136, awarded by the National Cancer Institute. cleophilic enolate 4 would serve in the relatively unexplored role of an electrophile in the above reaction. Indeed, when the epoxy enolate 4 (G= Li) was treated with Me2CuLi and the resulting product subjected to acidic hydrolysis, 6- methylcyclohex-2-enone (8, R= Me), the product of sN2'attack, was obtained in 65% yield, ...

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