Benzylidenemalonaldehydes: Synthesis of 4-aryl-2-dimethylamino-4H-1, 3-oxazine-5-carboxaldehyde

Z Arnold, D Dvořák

Index: Arnold, Zdenek; Dvorak, Dalimil Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 10 p. 2265 - 2269

Full Text: HTML

Citation Number: 8

Abstract

Abstract Reaction of substituted benzylidenemalonaldehydes Ia-Ic and thienylmethylenemalonaldehyde (Id) with dimethylcyanamide in boiling benzene afforded the corresponding 4-aryl-2-dimethylamino-4H-1, 3-oxazine-5-carboxaldehydes III. Electronic requirements for this cyclization reaction are discussed in relation with general rules and further applicability.