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Rapid and efficient synthesis of a fully functionalized synthon for the bottom half of the antiparasitic agent, ivermectin

ME Jung, Y Usui, CT Vu

Index: Jung, Michael E.; Usui, Yoshihiro; Vu, Chi Truc Tetrahedron Letters, 1987 , vol. 28, # 48 p. 5977 - 5980

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Citation Number: 35

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The preparation of the bottom half of ivermectin 3 in 10 steps and 9% overall yield is reported. ... Synthesis of a synthon for the bottom half of ivermectin with all the required functionality in the correct oxidation states, namely compounds 3, has been synthesized from 4 and 5 ...

Chemoselective cycloadditions of 3, 4-dialkoxyfurans and alkyl coumalates. Novel loss of aromaticity of two nonbenzenoid aromatic rings in a mild thermal process

[Jung, Michael E.; Street, Leslie J.; Usui, Yoshihiro Journal of the American Chemical Society, 1986 , vol. 108, # 21 p. 6810 - 6811]

Rapid and efficient synthesis of a fully functionalized synthon for the bottom half of the antiparasitic agent, ivermectin

Abstract

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