Efficient synthesis of 3??arylaminopyrroline??2??ones by the tandem reaction of anilines and β, γ??unsaturated α??ketoesters

YC Wu, L Liu, D Wang, YJ Chen

Index: Wu, Yan-Chao; Liu, Li; Wang, Dong; Chen, Yong-Jun Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 4 p. 949 - 955

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Citation Number: 25

Abstract

The development of synthetic methods for constructing pyrroles and their analogues has been of great interest to organic chemists for many years due to the presence of these structural units in a variety of biologically active natural products, medicinally relevant compounds, and functional materials [1-14]. It's worth mentioning that 3-arylaminopyrroline- 2-ones had been reported to exhibit anti-inflammatory, analgesic [15], antiphlogistic, and ...