Degradation of Tetrahydro-β-carbolines in the Presence of Nitrite: HPLC-MS Analysis of the Reaction Products
S Diem, B Gutsche, M Herderich
Index: Diem, Stefanie; Gutsche, Birgit; Herderich, Markus Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 12 p. 5993 - 5998
Full Text: HTML
Citation Number: 6
Abstract
Motivated by the identification of numerous novel tetrahydro-β-carboline-carboxylic acids in food samples, we studied the reactions of tetrahydro-β-carbolines in the presence of nitrosating agents. The anticipated formation of nitroso derivatives from unsubstituted tetrahydro-β-carbolines, and from tetrahydro-β-carboline-3-carboxylic acids was indicated by HPLC-MS/MS analysis and validated by the characteristic product ion spectra of the ...
Related Articles:
Synthesis and evaluation of β-carboline derivatives as inhibitors of human immunodeficiency virus
[Brahmbhatt, Keyur G.; Ahmed, Nafees; Sabde, Sudeep; Mitra, Debashis; Singh, Inder Pal; Bhutani, Kamlesh K. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 15 p. 4416 - 4419]
[Letellier; Fleury; Torreilles; Previero Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 4 p. 1265 - 1270]