Enaminones in a multicomponent synthesis of 4-aryldihydropyridines for potential applications in photoinduced intramolecular electron-transfer systems

NA Al-Awadi, MR Ibrahim, MH Elnagdi…

Index: Al-Awadi, Nouria A.; Ibrahim, Maher R.; Elnagdi, Mohamed H.; John, Elizabeth; Ibrahim, Yehia A. Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 441 - 447

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Citation Number: 14

Abstract

Abstract An efficient three component reaction with enaminones, primary amines and aldehydes resulted in easy access to 1, 4-dihydropyridines with different substituents at the 1-, 3-, 4-and 5-positions. Microwaves improved the reaction yield, reducing also considerably the reaction time and the amount of solvent used. Chiral primary amines gave chiral 1-substituted-1, 4-dihydropyridines. The 4-(1-naphthyl) and 4-(phenanthren-9-yl) ...