Unnatural amino acids. II. Congeners of DL-3-carboxy-4-methoxyphenylalanine

F Leonard, A Wajngurt, W Tschannen…

Index: Leonard,F. et al. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 478 - 481

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Citation Number: 6

Abstract

... The poor analgetic activity of this coni- pound could be directly correlated with its very poor gastrointestinal absorptions determined by the method of Hogben, et al.9 It is noteworthy that ring methyla- (7) P. Schwerin, SP Bessman, and H. Waelsch, J. Bid. Chem., 184, 37 (1950). ... The crystal- line previpitate was filtered off and dissolved in wat,er. The pH of the result,iiig solut,ioii was adjueted t,o 3.2 with 10%; NaOH. ... (b) see also H. Dubicki. F. Zielinaki, and I:. IV. ...

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