Reaction of Phosphonium Ylides and Aromatic Nitriles under Lewis Acid conditions: an Easy Access to Aryl-Substituted α-Methoxyacetophenones
B Camuzat-Dedenis, O Provot, H Moskowitz…
Index: Camuzat-Dedenis; Provot; Moskowitz; Mayrargue Synthesis, 1999 , # 9 p. 1558 - 1560
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Citation Number: 6
Abstract
Abstract: In the presence of lithium chloride, as Lewis acid, the reaction of methoxymethyltriphenylphosphonium ylide 1 with aromatic nitriles 2 as phenacyl cation equivalents gives access to the corresponding a-methoxyacetophenones 3 in good yields. Key words: a-methoxyacetophenones, aromatic nitriles, lithium chloride, phosphorus ylide
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