Chemische Berichte

Water??soluble tetraoxa [n. 1. n. 1] paracyclophanes: Synthesis and host??guest interactions in aqueous solution

F Diederich, K Dick, D Griebel

Index: Diederich, Francois; Dick, Klaus; Griebel, Dieter Chemische Berichte, 1985 , vol. 118, # 9 p. 3588 - 3619

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Citation Number: 43

Abstract

Abstract The synthesis of water-soluble tetraoxa [n. 1. n. 1] paracyclophanes 1c–8c and open-chained model compounds 14c and 15c is described. 1c–8c possess differently sized cavities of pronounced hydrophobic character as binding site for apolar guests in aqueous solution. In 1c–8c, spiropiperidinium rings locate the water-solubility providing quaternary ammonium nitrogens remote from the cavity. The synthesis of water-insoluble tetraoxa [n. ...