Highly efficient synthesis of isoquinolines via nickel-catalyzed annulation of 2-iodobenzaldimines with alkynes: evidence for dual pathways of alkyne insertion
RP Korivi, CH Cheng
Index: Korivi, Rajendra Prasad; Cheng, Chien-Hong Organic Letters, 2005 , vol. 7, # 23 p. 5179 - 5182
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Citation Number: 105
Abstract
A wide range of substituted isoquinolines were synthesized via a highly efficient nickel- catalyzed annulation of the tert-butyl imines of 2-iodobenzaldehydes and various alkynes; examination of the regiochemistry of isoquinolines synthesized indicates that there are two different alkyne insertion pathways for the catalytic reactions.
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