RhII2??Catalyzed Synthesis of α??, β??, or δ??Carbolines from Aryl Azides

AL Pumphrey, H Dong, TG Driver

Index: Pumphrey, Ashley L.; Dong, Huijun; Driver, Tom G. Angewandte Chemie - International Edition, 2012 , vol. 51, # 24 p. 5920 - 5923

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Citation Number: 52

Abstract

Carbolines and tetrahydrocarbolines are common structural motifs in pharmaceuticals and natural products.[1] b-Carboline and its saturated analog, tryptoline, are particularly prevalent [2, 3] and continue to inspire methods to efficiently access them.[4, 5] In contrast, methods to access the d-[6] or a-isomer [7] are uncommon despite the important biological properties exhibited by these carbolines. In addition to antibacterial and antiplasmodial ...