Regioselective synthesis of camptothecin

AVR Rao, JS Yadav, M Valluri

Index: Rao, A. V. Rama; Yadav, J. S.; Valluri, Muralikrishna Tetrahedron Letters, 1994 , vol. 35, # 21 p. 3613 - 3616

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Citation Number: 41

Abstract

Camptothecin (If, isolated by MC Wani and his coworkers1 from the bark of Camptotheta acuminta, has shown tremendous potential as an antitumor and antileukemic agent.'Off late Camptothecin and its anologs have emerged as the most promising compounds for the treatment of solid tumors. 3 Recent findings have shown that camptothecin demonstrated exceptionai antiretroviral activity at dose levels well tolerated by ceils which prompted its ...