Indium trifluoride-A Lewis acid catalyst for the addition of TMSCN to aldehydes in water
TP Loh, KC Xu, DSC Ho, KY Sim
Index: Loh, Teck-Peng; Xu, Kai-Chen; Ho, Diana Sook-Chiang; Sim, Keng-Yeow Synlett, 1998 , # 4 p. 369 - 370
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Citation Number: 28
Abstract
Cyanohydrins are versatile synthetic intermediates bearing two functional groups which can be easily manipulated into a wide range of other products such as α-hydroxy aldehydes, α-hydroxy ketones, β- hydroxy amines and α-amino acid derivatives.1 Accordingly, much attention has been focused on the development of new, versatile and practical methods for the synthesis of cyanohydrins including most recently the development of asymmetric version of this ...
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