Synthesis and study of antibacterial and antifungal properties of (2-thiocyanato-3-arylpropoxymethyl) oxiranes

PM Gorbovoi, GY Zagrichuk, AV Blinder…

Index: Gorbovoi; Zagrichuk; Blinder; Vlasik; Grishchuk Pharmaceutical Chemistry Journal, 1999 , vol. 33, # 1 p. 22 - 23

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Abstract

Previously, we have used a reaction between aryldia- zonium tetrafluoroborates with chloro(bromo, isothiocy- anato)propenes in the presence of sodium rhodanide (bro- mide) for the synthesis of a series of 2-thiocyanato(bromo, isothiocyanato)- 1 -aryl-3-chloro(bromo, isothiocyanato)pro- panes [1], among which are compounds possessing antimi- crobial activity [2, 3]. In continuation of the search for new antibacterial and an- tifungal agents among ...

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