Synthesis and In Vitro Activity Evaluation of 2′, 3′-C-Dimethyl Carbocyclic Nucleoside Analogues as Potential Anti-HCV Agents
OH Ko, JH Hong
Index: Nucleosides, Nucleotides and Nucleic Acids, , vol. 28, # 8 p. 761 - 771
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Citation Number: 5
Abstract
... Nucleosides Nucleotides Nucleic Acids, 27: 1186–1196. ... We can conclude that the dimethyl groups at 2′,3′-position are attributed to the inability of the nucleoside kinase to catalyze the initial phosphorylation of the nucleosides to their monophosphates. ...
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