Prodrug strategy for PSMA-targeted delivery of TGX-221 to prostate cancer cells
Y Zhao, S Duan, X Zeng, C Liu, NM Davies…
Index: Molecular Pharmaceutics, , vol. 9, # 6 p. 1705 - 1716
Full Text: HTML
Citation Number: 28
Abstract
... a novel formulation approach for improving site-specific drug delivery of a molecular-targeted prostate ... The synthetic small molecule TGX-221 (Figure 1) is a potent, selective, and cell membrane ... have been used as an effective drug delivery system for lipophilic molecules.(21-23 ...
Related Articles:
Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold
[Knight, Zachary A.; Chiang, Gary G.; Alaimo, Peter J.; Kenski, Denise M.; Ho, Caroline B.; Coan, Kristin; Abraham, Robert T.; Shokat, Kevan M. Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 17 p. 4749 - 4759]
Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold
[Bioorganic and Medicinal Chemistry, , vol. 12, # 17 p. 4749 - 4759]