A convenient and one??pot synthesis of 9??substituted carbazoles from primary amine hydrochlorides and 2, 5??dimethoxytetrahydrofuran
…, T Maruyama, K Harada, Y Omote
Index: Kashima, Choji; Hibi, Shigeki; Maruyama, Tatsuya; Harada, Kazuo; Omote, Yoshimori Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 913 - 916
Full Text: HTML
Citation Number: 21
Abstract
Abstract Carbazoles are the very important compounds in material science, nevertheless conventional syntheses required severe and complicated reaction conditions. In the process of preparation of pyrrole derivatives, we found that a primary amine hydrochloride 1 and 2, 5- dimethoxytetrahydrofuran 2 were refluxed in a benzenewater (100: 4 (v/v)) mixture to be obtained 9-substituted carbazole 5 in a high yield. This method is the one-pot synthesis of ...
Related Articles:
[Bandgar, Babasaheb P.; Adsul, Laxman K.; Lonikar, Shrikant V.; Chavan, Hemant V.; Shringare, Sadanand N.; Patil, Sachin A.; Jalde, Shivkumar S.; Koti, Basawaraj A.; Dhole, Nagesh A.; Gacche, Rajesh N.; Shirfule, Amol Journal of Enzyme Inhibition and Medicinal Chemistry, 2013 , vol. 28, # 3 p. 593 - 600]
[Uchiyama, Masanobu; Matsumoto, Yotaro; Nakamura, Shinji; Ohwada, Tomohiko; Kobayashi, Nagao; Yamashita, Natsuno; Matsumiya, Atsushi; Sakamoto, Takao Journal of the American Chemical Society, 2004 , vol. 126, # 28 p. 8755 - 8759]
Oxidative Pd (II)-catalyzed C− H bond amination to carbazole at ambient temperature
[Jordan-Hore, James A.; Johansson, Carin C. C.; Gulias, Moises; Beck, Elizabeth M.; Gaunt, Matthew J. Journal of the American Chemical Society, 2008 , vol. 130, # 48 p. 16184 - 16186]
[Fuerstner, Alois; Martin, Ruben; Krause, Helga; Seidel, Guenter; Goddard, Richard; Lehmann, Christian W. Journal of the American Chemical Society, 2008 , vol. 130, # 27 p. 8773 - 8787]
Alkylation with oxalic esters. Scope and mechanism
[Bergman, Jan; Norrby, Per-Ola; Sand, Peter Tetrahedron, 1990 , vol. 46, # 17 p. 6113 - 6124]