Kynurenic acid amides as novel NR2B selective NMDA receptor antagonists

I Borza, S Kolok, K Galgóczy, A Gere, C Horváth…

Index: Borza, Istvan; Kolok, Sandor; Galgoczy, Kornel; Gere, Aniko; Horvath, Csilla; Farkas, Sandor; Greiner, Istvan; Domany, Gyoergy Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 2 p. 406 - 409

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Citation Number: 23

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A novel series of kynurenic acid amides, ring-enlarged derivatives of indole-2-carboxamides, was prepared and identified as in vivo active NR2B subtype selective NMDA receptor antagonists. The synthesis and SAR studies are discussed. ... Starting from indole- and ...