Products from dehydration of dicarboxylic acids derived from anthranilic acid

P Wiklund, I Romero, J Bergman

Index: Wiklund, Per; Romero, Ivan; Bergman, Jan Organic and Biomolecular Chemistry, 2003 , vol. 1, # 19 p. 3396 - 3403

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Citation Number: 10

Abstract

Treatment of N-(carboxymethyl)-anthranilic acids 1 with several dehydrating agents, gave the cyclic ortho amides 6, or the 7-membered anhydrides 7. After reaction of N- (carboxymethyl)-anthranilic acid (1a) with acetic anhydride, a diacetylated fused diketopiperazine indole dimer (18) could be isolated. Dehydrations of 2, 2′-iminobis- benzoic acid led to the corresponding cyclic ortho amides 23. The dynamic behaviour of ...