Aromatic fluorination by silver-ion promoted decomposition of aryl diazo sulfides: efficient utilization of substoichiometric levels of fluoride ion

…, JP DiZio, JA Katzenellenbogen

Index: Haroutounian, Serkos A.; DiZio, James P.; Katzenellenbogen, John A. Journal of Organic Chemistry, 1991 , vol. 56, # 16 p. 4993 - 4996

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Citation Number: 18

Abstract

The thermal decomposition of aryl diazonium tetrafluoroborates or hexafluorophosphates (the Baltz-Schiemann reaction and variants, Scheme I) is widely used as a method for preparing aromatic fluoro compounds.'Within certain structural and functional constraints, yields vary from moderate to good. lb The Baltz-Schiemann reaction, however, is not well suited for fluorination with the short-lived, positron-emitting radionuclide fluorine-18 (tlIz= ...