Synthesis and biological activity of derivatives of 5-arylthiophene-2-carboxylic acids

VI Shvedov, OA Safonova

Index: Shvedov,V.I.; Safonova,O.A. Pharmaceutical Chemistry Journal, 1978 , vol. 12, # 11 p. 1448 - 1451 Khimiko-Farmatsevticheskii Zhurnal, 1978 , vol. 12, # 11 p. 53 - 56

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Abstract

Several thiophenecarboxylic acids and their derivatives are known to display bactericidal activity, including significant antituberculosis action [i]. Biological activity in many cases can be enhanced by the introduction of an aryl substituent [2-4]. In this context we have