Design and Scale-Up of Diels–Alder Reactions for the Practical Synthesis of 5-Phenylbicyclo [2.2. 2] oct-5-en-2-one

JA Funel, G Schmidt, S Abele

Index: Luo, Yunfei; Carnell, Andrew J. Journal of Organic Chemistry, 2010 , vol. 75, # 6 p. 2057 - 2060

Full Text: HTML

Citation Number: 18

Abstract

... Select a Journal or Book ... Organic ... It took three months starting with route finding until the delivery of 1 (2 × 1 kg batch) following the synthesis as depicted in Schemes 3 and 5. This material ensured the rapid start and execution of the downstream chemistry towards the API. ...

Related Articles:

Synthesis and chiroptical properties of 5, 7-dioxobicyclo [2.2. 2] oct-2-ene and bicyclo [2.2. 2] octane-2, 5-dione

[Hill, Richard K.; Morton, Gerald H.; Peterson, John R.; Walsh, James A.; Paquette, Leo A. Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5528 - 5533]

Rhodium/chiral diene-catalyzed asymmetric 1, 4-addition of arylboronic acids to arylmethylene cyanoacetates

[Tokunaga, Norihito; Otomaru, Yusuke; Okamoto, Kazuhiro; Ueyama, Kazuhito; Shintani, Ryo; Hayashi, Tamio Journal of the American Chemical Society, 2004 , vol. 126, # 42 p. 13584 - 13585]

Synthesis and chiroptical properties of 5, 7-dioxobicyclo [2.2. 2] oct-2-ene and bicyclo [2.2. 2] octane-2, 5-dione

[Hill, Richard K.; Morton, Gerald H.; Peterson, John R.; Walsh, James A.; Paquette, Leo A. Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5528 - 5533]

Synthesis and chiroptical properties of 5, 7-dioxobicyclo [2.2. 2] oct-2-ene and bicyclo [2.2. 2] octane-2, 5-dione

[Hill, Richard K.; Morton, Gerald H.; Peterson, John R.; Walsh, James A.; Paquette, Leo A. Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5528 - 5533]

More Articles...