(1R, 2R)-2-nitroxycyclohexan-1-ol: First example of a cyclohexyl based chiral auxiliary with nitroxy function as diastereoface discriminating group

…, S Pandiaraju, M Bakthadoss, K Muthukumaran

Index: Basavaiah, Deevi; Pandiaraju, Subramanian; Bakthadoss, Manickam; Muthukumaran, Kannan Tetrahedron Asymmetry, 1996 , vol. 7, # 4 p. 997 - 1000

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Citation Number: 16

Abstract

Spectral data for 4a: IR cm −1 : 1635, 1728, 3522; 1 H NMR (CDCl 3 ) (200 MHz) : & 0.72 (2d in the ratio 6 : 94, 3H, J = 6.8 Hz), & 0.97 (2d in the ratio 6 : 94, 3H, J = 6.6 Hz) 1.22–2.38 (m, 8H), 2.64 (m, 1H), 3.65 (s, 1H, OH), 4.84 (m, 1H), 5.04 & (2m, 1H), 7.18–7.38 (m, 3H), 7.52–7.68 (m, 2H); 13 C NMR (CDCl 3 ) (50 MHz) : 15.77, 16.95, 22.93, 23.22, 29.00, , 30.16, 35.22, , 73.41, , 80.88, 81.99, 125.62, , 127.64, 128.12, 140.70, 175.00 (the underlined chemical ...