Triggered Liposomal Release through a Synthetic Phosphatidylcholine Analogue Bearing a Photocleavable Moiety Embedded within the sn??2 Acyl Chain

AM Bayer, S Alam, SI Mattern??Schain…

Index: Bayer, Andrew M.; Alam, Shahrina; Mattern-Schain, Samuel I.; Best, Michael D. Chemistry - A European Journal, 2014 , vol. 20, # 12 p. 3350 - 3357

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Citation Number: 9

Abstract

Abstract Liposomes represent promising carriers for drug delivery applications. To maximize this potential, there has been significant interest in developing liposomal systems encapsulating molecular cargo that are highly stable until their contents are released remotely in a controlled manner. Herein, we describe the design, synthesis, and analysis of a photocleavable analogue of the ubiquitous lipid phosphoatidylcholine (PC) for the ...