Synlett

Unusual t-buli induced ortholithiation versus halogen-lithium exchange in bromopyridines: Two alternative strategies for functionalization

P Pierrat, P Gros, Y Fort

Index: Synlett, , # 13 p. 2319 - 2322

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Citation Number: 19

Abstract

... Synlett 2004(13 ... The absence of detection of pyridine in the reaction medium ruled out an intermolecular lithiation between 3-lithiopyridine and unreacted 1. Indeed, pyridine is sluggishly metallated by t-BuLi [13] and should be accumulated ... See: Gros P. Fort Y. Caubère PJ Chem ...