Synlett

Gas-phase pyrolysis in organic synthesis: rapid green synthesis of 4-quinolinones

NA Al-Awadi, IA Abdelhamid, AM Al-Etaibi…

Index: Al-Awadi, Nouria A.; Abdelhamid, Ismail Abdelshafy; Al-Etaibi, Alya M.; Elnagdi, Mohamed Hilmy Synlett, 2007 , # 14 p. 2205 - 2208

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Citation Number: 11

Abstract

Abstract Gas-phase pyrolysis of aminomethylene Meldrum's acid derivatives gave quinolinones and/or amines depending on the nature of arylamino moiety. Effect of substituent on reaction rate and nature of pyrolysis products supports the suggested intramolecular nucleophilic substitution reaction via initially formed keteneamine intermediate.