The Journal of Organic Chemistry

Improved chiral derivatizing agents for the chromatographic resolution of racemic primary amines

WH Pirkle, KA Simmons

Index: Pirkle, William H.; Simmons, Kirk A. Journal of Organic Chemistry, 1983 , vol. 48, # 15 p. 2520 - 2527

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Citation Number: 86

Abstract

Materials. Inorganic and organic reagents used were all of the highest commercial grade and used without further purification. A solution of HC1 in ethanol-water (9010 v/v) was prepared by mixing 35% aqueous HC1 or gaseous HCl with appropriate amount of 99% ethanol and water. The concentration was confirmed by alkalimetry.