Stoffwechselprodukte von Mikroorganismen. 101. Mitteilung. Synthese der trans??5??Hydroxy??3??methylpenten??(2)??säure (trans?螃?2??Anhydromevalonsäure)

W Keller??Schierlein, J Widmer…

Index: Keller-Schierlein,W. et al. Helvetica Chimica Acta, 1972 , vol. 55, # 1 p. 198 - 205

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Citation Number: 7

Abstract

Abstract trans-Δ 2-Anhydromevalonic acid (XVII) was prepared by a Wittig reaction, starting from (4-tetrahydro-2-pyranyloxy)-2-butanone. On the other hand, the corresponding 4- acetoxy-2-butanone gave, under similar conditions, the cyclohexene derivative V, explainable by a twofold Michael addition of the Wittig reagent to methyl vinyl ketone, followed by an intramolecular alcol condensation.

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