A Practical Method for the Reformatsky Reaction of Aldehydes
A Chattopadhyay, A Salaskar
Index: Chattopadhyay, Angshuman; Salaskar, Avinash Synthesis, 2000 , # 4 p. 561 - 564
Full Text: HTML
Citation Number: 28
Abstract
Abstract: Reformaksky reaction of aliphatic aldehydes has been performed successfully by the addition of BF3• OEt2 to a stirred suspension of aldehyde, bromo ester and Zn dust in aqueous THF. For aromatic aldehydes, addition of benzoyl peroxide is also required to effect the reaction. Key words: aqueous condition, boron trifluoride etherate, stereoselectivity, chemoselectivity, radical chain mechanism.
Related Articles:
Titanocene (III)-promoted Reformatsky additions
[Parrish; Shelton, Daniel R.; Little, R. Daniel Organic Letters, 2003 , vol. 5, # 20 p. 3615 - 3617]
Titanocene (III)-promoted Reformatsky additions
[Parrish; Shelton, Daniel R.; Little, R. Daniel Organic Letters, 2003 , vol. 5, # 20 p. 3615 - 3617]
[Kiyooka, Syun-ichi; Nakata, Masumi Chemistry Letters, 1988 , p. 721 - 722]
2, 2-Di (ethoxy) vinyllithium: Reactions with carbonyl compounds
[Hiouni, Abdelaziz; Duhamel, Lucette Tetrahedron Letters, 1996 , vol. 37, # 31 p. 5507 - 5510]
[Miura, Katsukiyo; Sato, Hiroshi; Tamaki, Kentaro; Ito, Hajime; Hosomi, Akira Tetrahedron Letters, 1998 , vol. 39, # 17 p. 2585 - 2588]