Tetrahedron letters

Synthesis of tetrasubstituted Zn (II)-phthalocyanines carrying four carboranyl-units as potential BNCT and PDT agents

…, G Chiti, C Fabris, P Colautti, G Jori, G Roncucci

Index: Giuntini, Francesca; Raoul, Yann; Dei, Donata; Municchi, Moira; Chiti, Giacomo; Fabris, Clara; Colautti, Paolo; Jori, Giulio; Roncucci, Gabrio Tetrahedron Letters, 2005 , vol. 46, # 17 p. 2979 - 2982

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Citation Number: 46

Abstract

The synthesis of two tetrasubstituted zinc (II) phthalocyanines carrying four carbon–carbon linked o-carboranyl-units (40 boron atoms, 27.5% boron by weight) is presented. In an in vitro model test the new compounds showed a good photosensitizing efficiency, that encourages further studies for their evaluation as possible BNCT–PDT sensitizers.