An adventitious synthesis of a 5-methylimidazo [4, 5-c] pyridine derivative
P Barraclough, R Iyer, JC Lindon, JM Williams
Index: Barraclough; Iyer; Lindon; Williams Tetrahedron Letters, 1986 , vol. 27, # 49 p. 5997 - 6000
Full Text: HTML
Citation Number: 7
Abstract
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... At 210° in the melt 2-(4-Cyano-2-methoxyphenyl)-1 -imidazo[4,5- ]pyridine( ) undergoes isomerization to give 2-(4-cyano-2-hydroxyphenyl)-5-methylimidazo[4,5- ]pyridine ( ). ... At 210° in the melt 2 undergoes an O → N methyl migration. ... Prepared by the following route:- a. NaNO 2 , ...
Related Articles:
New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists
[Yea, Christopher M.; Allan, Christine E.; Ashworth, Doreen M.; Barnett, James; Baxter, Andy J.; Broadbridge, Janice D.; Franklin, Richard J.; Hampton, Sally L.; Hudson, Peter; Horton, John A.; Jenkins, Paul D.; Penson, Andy M.; Pitt, Gary R. W.; Riviere, Pierre; Robson, Peter A.; Rooker, David P.; Semple, Graeme; Sheppard, Andy; Haigh, Robert M.; Roe, Michael B. Journal of Medicinal Chemistry, 2008 , vol. 51, # 24 p. 8124 - 8134]