The Journal of Organic Chemistry

Decarboxylation of 1-aminocyclopropanecarboxylic acid and its derivatives

G Vaidyanathan, JW Wilson

Index: Vaidyanathan, Ganesan; Wilson, Joseph W. Journal of Organic Chemistry, 1989 , vol. 54, # 8 p. 1810 - 1815

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Citation Number: 11

Abstract

The question of whether the title compounds could be decarboxylated to cyclopropanone derivatives was answered in the affirmative by the following observations.(1) Compound 1 la was decarboxylated by 1, 2, 3-indantrione in acetonitrile, benzene, or methanol. The initially formed intermediate could be trapped by N-phenylmaleimide (to form 31, by diethyl azodicarboxylate (to form an unstable adduct), by ninhydrin itself (to form 5) or by a proton ...