Tetrahedron

Improved synthesis of three brominated analogues of the potent environmental mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2 (5H)-furanone (MX)

M Lloveras, I Ramos, E Molins, A Messeguer

Index: Tetrahedron, , vol. 56, # 21 p. 3391 - 3397

Full Text: HTML

Citation Number: 8

Abstract

... Tetrahedron. Volume 56, Issue 21, 19 May 2000, Pages 3391–3397. ... tetrahydrofuran/water followed by treatment with potassium bicarbonate, BMX-3 was formed in yields lower than 5%. Conversely, when this cyclisation was performed in 48% hydrobromic acid, 21 the expected ...