Direct Method for Carbon–Carbon Bond Formation: The Functional Group Tolerant Cobalt??Catalyzed Alkylation of Aryl Halides

M Amatore, C Gosmini

Index: Amatore, Muriel; Gosmini, Corinne Chemistry - A European Journal, 2010 , vol. 16, # 20 p. 5848 - 5852

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Citation Number: 55

Abstract

Modern transition-metal-catalyzed reactions have been shown to be of indispensable value for organic synthesis.[1] In particular, the cross-coupling of alkyl halides, including problematic unactivated alkyl halides, have now emerged as promising candidates to complement and extend the scope of the traditional Friedel–Crafts alkylation.[2, 3] The incorporation of a new alkyl chain on an aromatic moiety often proceeds by the metal- ...