Tertiary amide rotation in a nanoscale host

…, L Moisan, D Ajami, J Rebek

Index: Salvio, Riccardo; Moisan, Lionel; Ajami, Dariush; Rebek Jr., Julius European Journal of Organic Chemistry, 2007 , # 16 p. 2722 - 2728

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Citation Number: 5

Abstract

Abstract A self-assembled cylindrical capsule provides a nanoscale environment that affects the rotational barriers of tertiary amides. Measurements of the activation energies for the rotations and behaviors of the amides inside the capsule were determined by using 1 H NMR spectroscopic methods in deuterated mesitylene solution. For amides 3–8, rotation rates can decrease or increase in the capsule by up to an order of magnitude from those ...