Microwave-assisted protocols for the expedited synthesis of pyrazolo [1, 5-a] and [3, 4-d] pyrimidines

RN Daniels, K Kim, EP Lebois, H Muchalski…

Index: Tetrahedron Letters, , vol. 49, # 2 p. 305 - 310

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Citation Number: 54

Abstract

... Tetrahedron Letters. Volume 49, Issue 2, 7 January 2008, Pages 305–310. Cover image Cover image. ... Conversion to the chloride with POCl 3 and subsequent S N Ar with an amine provides pyrazolo[3,4-d]pyrimidine 2 in two operations without isolation of the chloride. 3 and 4. ...