Regioselectivity in the Addition of 1, 3-Dipolarophiles to 6-Aryl-1, 5-diazabicyclo [3.1. 0] hexanes

AP Molchanov, DI Sipkin, YB Koptelov, J Kopf…

Index: Molchanov; Sipkin; Koptelov; Kopf; Kostikov Russian Journal of Organic Chemistry, 2004 , vol. 40, # 1 p. 67 - 78

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Citation Number: 15

Abstract

Abstract Thermolysis of 6-aryl-1, 5-diazabicyclo [3.1. 0] hexanes in the presence of 1, 3- dipolarophiles having an unsymmetrically substituted double C= C bond (such as N- arylimides derived from 2-aryl-substituted maleic, citraconic, and itaconic acids, ethyl propynoate, aryl isocyanates, and aryl isothiocyanates) leads to formation of the corresponding 1, 3-dipolar cycloaddition products. The reaction is regioselective, and in ...