Organic reactions in ionic liquids: a simple and highly regioselective N-substitution of pyrrole
ZG Le, ZC Chen, Y Hu, QG Zheng
Index: Le, Zhang-Gao; Chen, Zhen-Chu; Hu, Yi; Zheng, Qin-Guo Synthesis, 2004 , # 12 p. 1951 - 1954
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Citation Number: 20
Abstract
Abstract In ionic liquids [Bmim][PF 6] or [Bmim][BF 4], pyrrole replaced the halogen atom of an alkyl halide to give the corresponding N-substituted pyrrole in excellent yield. Benzenesulfonyl chloride, p-methylbenzenesulfonyl chloride and benzoyl chloride reacted similarly with pyrroles to afford the N-substituted pyrroles in quantitative yield. Michael addition reaction of pyrrole with electrophilic olefins was completed in a highly ...
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