Carbohydrate research

Synthesis and characterization of mannosylated oligoribonucleotides

Y Zhao, K Tram, H Yan

Index: Zhao, Yuyan; Tram, Kha; Yan, Hongbin Carbohydrate Research, 2009 , vol. 344, # 16 p. 2137 - 2143

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Citation Number: 5

Abstract

Oligoribonucleotide (RNA)–carbohydrate conjugates bearing mono-and divalent mannosides were readily obtained using 3, 4-diethoxy-3-cyclobutene-1, 2-dione as the linking agent in the presence of trace amount of triethylamine. The glycoconjugates were purified by HPLC and characterized by electrospray mass spectroscopy.