Tetrahedron Letters

Catalyst-free transformations of diethyl 2-ethoxymethylenemalonate and diethyl polyfluorobenzoylmalonates in water

DN Bazhin, YS Kudyakova, YV Burgart, VI Saloutin

Index: Bazhin, Denis N.; Kudyakova, Yulia S.; Burgart, Yanina V.; Saloutin, Victor I. Tetrahedron Letters, 2012 , vol. 53, # 15 p. 1961 - 1963

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Citation Number: 5

Abstract

The unusual transformation of diethyl 2-ethoxymethylenemalonate into triethyl 1, 3, 5- benzenetricarboxylate is described. This one-pot reaction proceeds in water without any catalyst in a good yield. One of the proposed intermediates of this process is also used under similar conditions to give the desired trisubstituted benzene. A catalyst-free, efficient, practical, and convenient process in water based on deethoxycarbonylation has been ...

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